| Primary Identifier | MGI:2445835 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Serpina5 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 3.6 kb fragment containing a portion of exon 2, exons 3 and 4, and a portion of exon 5, was replaced by with a neomycin selection cassette. No transcript was detected in the testes or ovaries of homozygous mutant mice by RT-PCR analysis. Both Western blot analysis and ELISA indicated an absence of endogenous protein in the testes of homozygous mutant mice. |