Primary Identifier | MGI:2445968 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Evx2 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
description | This allele exists only in mice carrying Hoxd13tm3Ddu |
molecularNote | Translation of both the Evx2 and Hoxd13 loci was disrupted by the insertion of stop codons at base pairs 110 and 58 of the respective open reading frames. In addition, the targeting construct contained a floxed neo cassette inserted into the intergenic region as well as 153 bp deletion of Hoxd13. |