Primary Identifier | MGI:2445461 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Pax8 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exon 3 with an in-frame cre recombinase and frt-flanked neo cassette via homologous recombination. The targeted mutation deletes the N-terminal portion of the paired domain, which is essential for DNA-binding. |