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Allele : Gja1<tm1Kwi> gap junction protein, alpha 1; targeted mutation 1, Klaus Willecke

Primary Identifier  MGI:2445468 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gja1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites flanking the coding region of the gene were introduced into exon 2 and a floxed tk-neo cassette and lacZ gene were inserted into the downstream region via homologous recombination. Northern blot analysis confirmed expression of the mutant allele, and Western blot analysis showed protein expression is similar in mutant animals compared to wild-type.
  • mutations:
  • Insertion
  • synonyms:
  • Cx43<fl[lacZ]>,
  • Cx43::LacZ,
  • Cx43::LacZ,
  • Cx43<fl>,
  • 3lox,
  • 3lox,
  • Cx43<fl[lacZ]>,
  • Cx43<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

118 Publication categories