Primary Identifier | MGI:2445978 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(K5-Ptgs2)19Kmd |
Strain of Origin | NMRI | Is Recombinase | false |
Is Wild Type | false |
description | Seven founder animals were constructed and bred successfully. The founders are designated lines 4, 19, 29, 663, 667, 675, and 678. Line 19 exhibits weak transgene expression. |
molecularNote | The transgene is composed of a full length Ptgs2 cDNA without the 3' untranslated region fused to a bovine keratin 5 (K5) promoter. Transgene expression was confirmed by RT-PCR analysis of stratified epithelial tissues. |