Primary Identifier | MGI:2445981 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(2Hoxd11-Hoxd13)2Ddu |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Hoxd11, Hoxd12, Hoxd13, and regions VIII through XI were deleted via trans-allelic meiotic recombination (TAMERE). The deletion was accomplished by recombination of a single loxP site in the intergenic region between Evx2 and Hoxd13 (Evx2/Hoxd13tm1.1Ddu) and a single loxP on the opposite chromosome downstream of region XI (Hoxdtm5Ddu). |