| Primary Identifier | MGI:2446091 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(IT6)5Kka |
| Strain of Origin | (C57BL/6J x DBA/2J)F2 | Is Recombinase | false |
| Is Wild Type | false |
| description | Two transgenic founders, designated IT6-M and IT6-F, were created. The expression pattern of both IT6-M and IT6-F were similar except for occasional expression in lungs and liver of IT6-F.
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| molecularNote | 2.7 kb of SV40 sequences, including the large T and small t antigen coding regions and polyadenylation signal, were fused to a 6 kb mouse Inha promoter fragment and used for the transgene. RT-PCR analysis showed expression of the SV40 transgene in gonads, adrenal glands, brains, pituitary, spleen, kidney, epididymis, and submandibular gland. |
