Primary Identifier | MGI:2446340 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Prrx1-Hand2)4Eno |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene consists of a mouse Prrx1 promoter fused to a mutant Hand2 cDNA deleted for residues 1-90 and 155-217. The mouse Prrx1 promoter was used to drive transgene expression in the forelimb bud and anterior mesoderm of the hindlimb in E10.5 embryos. The Hand2 construct also contains an N-terminal Myc epitope tag and a 3' human growth hormone polyadenylation signal. |