Primary Identifier | MGI:2446639 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Camk2a-Fyn)1Kndl |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | An Fyn (isoform B) cDNA and Camk2a promoter were used for the transgene. Transgene expression was confirmed in the forebrain of 1-month old transgenic animals by Northern blot and in situ hybridization. Transgenic RNA is expressed at 4 times the level of endogenous Fyn RNA. 8 kb of Camk2a promoter sequences directs transgene expression in postnatal forebrain neurons. |