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Allele : Tg(Tagln-tTA)1Mrab transgene insertion 1, Marlene Rabinovitch

Primary Identifier	MGI:2447082	Allele Type	Transgenic
Attribute String	Transactivator	Gene	Tg(Tagln-tTA)1Mrab
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

Sequence encoding a tetracycline transactivator was adjoined to the smooth muscle cell specific transgelin promoter. The promoter was reported to drive expression in the aorta, but not in the heart, lung, kidney, bladder, intestine, or stomach.

mutations:
Insertion

synonyms:
tTA+,
SM22alpha- tTA,
tTA+,
SM22alpha- tTA

earliestPublication:
Ju H, et al. (2001) Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice. Proc Natl Acad Sci U S A 98(13):7469-74

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

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