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Allele : Tg(tTA)1Pjln transgene insertion 1, Peter J Nielsen

Primary Identifier	MGI:2447131	Allele Type	Transgenic
Attribute String	Transactivator	Gene	Tg(tTA)1Pjln
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

The transgenic construct contained sequence encoding a doxycycline-responsive tetracycline transactivator. Expression was driven in the thymus and in bone marrow by a minimal promoter adjoined to an intronic mu heavy chain enhancer.

mutations:
Insertion

synonyms:
Emu-tTA,
muE-tTA,
muE-tTA,
tTA/mu chain,
tTA/mu chain,
Emu-tTA

earliestPublication:
Hess J, et al. (2001) The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development. Mol Cell Biol 21(5):1531-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

11 Publication categories

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