| Primary Identifier | MGI:2447147 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Sox5 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a lacZ-neo-derived cassette into the fifth coding exon of the gene corresponding to the N terminus of the coiled coil domain. Absence of gene expression in homozygous animals was confirmed by Northern blot analysis of whole embryo RNA. X-gal staining of mutant embryos revealed lacZ expression in cartilage tissue. |
