| First Author | Zagani R | Year | 2016 |
| Journal | Leuk Res | Volume | 40 |
| Pages | 100-2 | PubMed ID | 26654706 |
| Mgi Jnum | J:320633 | Mgi Id | MGI:6875260 |
| Doi | 10.1016/j.leukres.2015.11.011 | Citation | Zagani R, et al. (2016) Deletion of the putative tumor suppressor gene, G0s2, does not affect progression of Emu-Myc driven lymphomas in mice. Leuk Res 40:100-2 |
| abstractText | Several recent reports have suggested that the G0/G1 switch gene 2 (G0S2) is a potential tumor suppressor in leukemia. Here we show that deletion of the G0s2 gene in mouse does not affect the latency of cancer progression in the Emu-Myc model of lymphoma. Our findings do not rule out the possibility that G0S2 may be playing a role in other forms of leukemia, but clearly show that the commonly used Emu-Myc transgenic is not the correct model to conduct studies on G0s2. |
