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Allele : Tg(PDGFB-PSEN1)1Jhd transgene insertion 1, John Hardy

Primary Identifier  MGI:2447324 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(PDGFB-PSEN1)1Jhd
Strain of Origin  SW x (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A PDGFB promoter fused to a human PSEN1 cDNA, which includes the intron between exons 4 and 5, was used for the transgene. The PDGFB promoter was used to drive transgene expression in neurons. Transgene expression was confirmed by Northern and Western blot analysis of brain extracts derived from transgenic animals.
  • mutations:
  • Insertion
  • synonyms:
  • PS1wt,
  • PS1wt
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories