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Allele : Gnaz<tm1Lfb> guanine nucleotide binding protein, alpha z subunit; targeted mutation 1, Lawrence F Brass

Primary Identifier  MGI:2447341 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gnaz
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  The coding region of exon 1 was replaced with a cassette containing sequence encoding enhanced GFP (EGFP) followed by neo. Normal protein was undetected by Western blot analysis of brain and platelet samples obtained from homozygous mutant mice. EGFP transcript was present in brain tissue and fluorescence was detected in platelets and megakaryocytes.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gz alpha(-),
  • Gz alpha(-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele