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Allele : Tg(CAG-Ncoa6*)#Hwl transgene insertion, Han-Woong Lee

Primary Identifier  MGI:2447471 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CAG-Ncoa6*)#Hwl
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a hemagglutinin (HA)-tagged fragment of Ncoa6 encoding amino acids 849-929, in which the N-terminal LXXLL motif is mutated to LXXAA, under the control of the chicken beta-actin promoter linked to a human cytomegalovirus immediate-early enhancer (CAG). This mutation abolishes receptor interactions. Four lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • DN1/m,
  • DN1/m,
  • Tg(ACTB-Ncoa6)2Hwl,
  • Tg(ACTB-Ncoa6)2Hwl
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories