Primary Identifier | MGI:2447471 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CAG-Ncoa6*)#Hwl |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of a hemagglutinin (HA)-tagged fragment of Ncoa6 encoding amino acids 849-929, in which the N-terminal LXXLL motif is mutated to LXXAA, under the control of the chicken beta-actin promoter linked to a human cytomegalovirus immediate-early enhancer (CAG). This mutation abolishes receptor interactions. Four lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled. |