| Primary Identifier | MGI:2447844 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Cit |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 of the endogenous locus was replaced with a cassette containing Beta-gal and neo genes, resulting in an isoform-specific mutation. Exon 2 is the second coding exon of the Citron-K isoform and is far upstream of the Citron-N trascriptional start site. Western blot analysis of cerebral, splenic, and thymic tissues inidicated an absence of the Citron-K isoform and showed normal levels of the Citron-N isoform in homozygous mutant mice. |
