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Allele : Bmp3<tm1Kml> bone morphogenetic protein 3; targeted mutation 1, Karen M Lyons

Primary Identifier  MGI:2448071 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bmp3
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A 3.8 kb fragment containing exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded most of the precursor region, the proteolytic processing site, and two thrids of the mature region. RT-PCR analysis indicated an absence of normal transcript in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bmp3<->,
  • Bmp3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele