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Allele : Tg(CKMM-tTA)A3Rhvh transgene insertion A3, R Hooft van Huijsduijnen

Primary Identifier	MGI:2448088	Allele Type	Transgenic
Attribute String	Transactivator	Gene	Tg(CKMM-tTA)A3Rhvh
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

Sequence encoding the tTA transactivator was placed under the control of the human creatine kinase, muscle promoter, which drove strong expression in striated muscle and weak expression in heart and lung tissue.

mutations:
Insertion

synonyms:
MCK-tTA,
Pmck-tTA,
Pmck-tTA,
MCK-tTA

earliestPublication:
Ghersa P, et al. (1998) Highly controlled gene expression using combinations of a tissue-specific promoter, recombinant adenovirus and a tetracycline-regulatable transcription factor. Gene Ther 5(9):1213-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

19 Publication categories

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