| Primary Identifier | MGI:2447529 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Rnf2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The authors generated a hypomorphic Rnf2 allele using gene targeting. No genomic sequence was deleted. However, a Neo cassette and 0.8 kb of one of the homology arms were inserted between exons 3 and 4. The inserted sequence was from 3' UTS. Protein levels in the homozygous mutant were 30% of those in the heterozygous mutant. |
