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Allele : Tg(Mpz)80.3Wra transgene insertion 80.3, Lawrence Wrabetz

Primary Identifier	MGI:2447696	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Mpz)80.3Wra
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

The entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Transgenic line 80.3 carries 2 copies of the integrated transgene. Transgene expression is approximately 0.3-fold that of the endogenous protein.

mutations:
Insertion

synonyms:
Tg80.3,
Tg80.3

earliestPublication:
Wrabetz L, et al. (2000) P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol 148(5):1021-34

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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