| Primary Identifier | MGI:2448259 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TTR-FOXM1)1Rhc |
| Strain of Origin | CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Three transgenic founders, T38, T69, and T70, were created. Founder T38 exhibited the highest level of transgene expression and was used for further analysis. |
| molecularNote | The transgene consists of a TTR promoter and 2.6 kb of human FOXM1 sequence fused to TTR exon 2. The TTR regulatory region consists 3 kb of the TTR promoter, exon 1, and exon 2. This promoter construct targets transgene expression to hepatocytes. |
