| Primary Identifier | MGI:2448465 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cnmd |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The endogenous locus was disrupted by the insertion of a nonsense mutation in codon 21 (exon 1) and with the replacement of exon 3 with a neomycin selection cassette. Northern blot analysis of rib cartilage RNA and Western blot analysis of whole rib extract indicated an absence of normal transcript and protein in homozygous mutant mice. |