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Allele : Spib<tm1Mcs> Spi-B transcription factor (Spi-1/PU.1 related); targeted mutation 1, M Celeste Simon

Primary Identifier  MGI:2448991 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spib
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of the DNA-binding domain-containing exon 6 and part of intron 5 with a PGK-neo cassette via homologous recombination. Northern blot analysis of homozygous mutant splenocyte RNA (using a full-length Spib cDNA probe) confirmed the absence of gene expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Spi-B-,
  • Spi-B-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories