Primary Identifier | MGI:2448991 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Spib |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of the DNA-binding domain-containing exon 6 and part of intron 5 with a PGK-neo cassette via homologous recombination. Northern blot analysis of homozygous mutant splenocyte RNA (using a full-length Spib cDNA probe) confirmed the absence of gene expression. |