| Primary Identifier | MGI:2448161 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Xdh |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A self-excising neomycin resistance cassette was inserted into exon 3 of the endogenous gene. The targeting construct was comprised of sequence encoding GFP followed by a floxed region containing a mouse testes-specific Ace promoter fused to the cre recombinase and neomycin resistance genes. The floxed region undergoes self-excision during spermiogenesis, resulting in the production of protein encoded by exons 1 and 2 and a 5' portion of exon 3 fused to GFP. |
