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Allele : Tg(Mt1-GHRH)1Reh transgene insertion 1, Robert E Hammer

Primary Identifier	MGI:2448617	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Mt1-GHRH)1Reh
Strain of Origin	(C57BL/6 x SJL)F2	Is Recombinase	false
Is Wild Type	false

description	11 founder animals were created which sucessfully expressed human GHRH.
molecularNote	A mouse Mt1 promoter fused to a human GHRH minigene was used for the transgene. Northern blot analysis of transgenic livers confirmed expression of human GHRH mRNA.

mutations:
Insertion

synonyms:
MT-hGHRH,
MT-hGHRH

earliestPublication:
Hammer RE, et al. (1985) Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature 315(6018):413-6

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

17 Publication categories

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