Primary Identifier | MGI:2450291 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(KRT18-cre/ERT2)1Rgo |
Strain of Origin | FVB/N | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain inserted into exon 7 of human KRT18. Human KRT18 regulatory sequences were used to drive transgene expression in epithelial cells. |