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Allele : Nfia<tm1Rmg> nuclear factor I/A; targeted mutation 1, Richard M Gronostajski

Primary Identifier  MGI:2449024 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfia
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of 219 bp of exon 2 and the 3' splice acceptor with a PGK-neo cassette via homologous recombination. The mutant allele generates a fusion between exons 1 and 3 resulting in an out-of-frame transcript with a nonsense codon in exon 3. The mutant allele was verified by RT-PCR and sequence analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nfia<->,
  • Nfia<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

28 Publication categories