| First Author | Weber T | Year | 2019 |
| Journal | Eur J Immunol | Volume | 49 |
| Issue | 1 | Pages | 192-194 |
| PubMed ID | 30359469 | Mgi Jnum | J:267281 |
| Mgi Id | MGI:6260223 | Doi | 10.1002/eji.201847863 |
| Citation | Weber T, et al. (2018) A novel allele for inducible Cre expression in germinal center B cells. Eur J Immunol |
| abstractText | The germinal center reaction is essential for efficient humoral immunity, but it can also give rise to B cell lymphomas. Cre/loxP-mediated conditional gene knock-out or knock-in can be used for the genetic manipulation of germinal center B cells in vivo. Here we present a novel allele, Cgamma1-CreERT2, that allows for timed activation of Cre recombinase in a small fraction of germinal center B cells. This allele will be useful to study normal and malignant germinal center B cell development in vivo. |
