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Allele : Grip1<tm1Paw> glutamate receptor interacting protein 1; targeted mutation 1, Anthony Pawson

Primary Identifier  MGI:2449094 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Grip1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3.6 kb fragment was replaced with a beta-galactosidase gene followed by a floxed neo gene. The deleted region included a 3' portion of the exon encoding the first PDZ domain. No full length protein was detected by Western blot analysis of protein extracts obtained from homozygous mutant embryos. Beta-galactosidase staining indicated that the reporter gene was expressed via the endogenous promoter.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GRIP1<->,
  • GRIP1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories