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Allele : Psen1<tm2Shn> presenilin 1; targeted mutation 2, Jie Shen

Primary Identifier  MGI:2449304 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Psen1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A single loxP site was inserted into intron 1 and a loxP-flanked hygromycin and thymidine kinase selection cassette was inserted into intron 3. The drug selection cassette was removed in ES cells by transient Cre expression in ES cells prior to the production of mice. The final allele has single loxP sites flanking exons 2 and 3.
  • mutations:
  • Insertion
  • synonyms:
  • Psen1<f>,
  • Psen1<f>,
  • fPsen1,
  • PS1<C>,
  • Presenilin 1 floxed,
  • fPS1,
  • PS1<C>,
  • fPS1,
  • fPsen1,
  • Presenilin 1 floxed
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

52 Publication categories