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Allele : Hprt1<tm1(ACTB-Epor)Unc> hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, University of North Carolina

Primary Identifier  MGI:2450106 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Hprt1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct containing human beta actin promoter sequence adjoined to a cDNA fragment encoding a truncated erythropoietin receptor lacking 91 carboxy terminal amino acids was inserted at the endogenous locus via homologous recombination. An Hprt rescue technique using E14TG2a ES cells was used for selection to achieve a single copy insertion.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • tEpoR,
  • tEpoR
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories