| Primary Identifier | MGI:2449204 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(TIE2-lacZ)182Sato |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| description | In embryonic and adult transgenic mice on an FVB/N background, LacZ is expressed specifically in vascular endothelial cells. |
| molecularNote | The transgene consists of a mouse Tek promoter (2.1 kb HindIII segment including most of exon1), a lacZ reporter gene, a Tek1 enhancer element, and an SV40 polyadenylation sequence. The enhancer element is 1.7 kb genomic sequence (XhoI-KpnI restriction fragment) from inside the 5' half of intron 1. Expression was driven in endothelial cells. |
