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Allele : Lrp2<tm1Tew> low density lipoprotein receptor-related protein 2; targeted mutation 1, Thomas E Willnow

Primary Identifier  MGI:2449765 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Lrp2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  3 exons were flanked by a 5' floxed neo cassette and a 3' single loxP site. The most 3' exon in the floxed region encodes the membrane anchor of the receptor. Western blot analysis of kidney tissue obtained from homozygous mutant mice indicated that a protein product was produced by the floxed allele.
  • mutations:
  • Insertion
  • synonyms:
  • megalin<lox>,
  • megalin<lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

37 Publication categories