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Allele : Commd10<Tg(Vav1-icre)A2Kio> COMM domain containing 10; transgene insertion A2, Dimitris Kioussis

Primary Identifier  MGI:2449949 Allele Type  Transgenic
Attribute String  Null/knockout, Recombinase Gene  Commd10
Strain of Origin  (CBA/Ca x C57BL/10)F2 Is Recombinase  true
Is Wild Type  false
molecularNote  This transgene expresses Cre recombinase under the control of a vav promoter. This promoter was shown to be active in lymph nodes, thymus, spleen, Peyer's patches, intestinal cryptopatches, ovaries and testes. Line A2 inserted into the gene at 47022629-47022630 (Build GRCm38/mm10). The insetion results in a functional knock-out in homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • Vav-cre,
  • Tg(Vav1-icre)A2Kio,
  • Tg(Vav1-cre)1Kio,
  • Vav-iCre,
  • Vav-cre,
  • Vav1-Cre,
  • Tg(Vav1-cre)A2Kio,
  • Tg(Vav1-cre)A2Kio,
  • Tg(Vav1-icre)A2Kio,
  • VavCre<deBoer>,
  • Vav-iCre,
  • Vav1-Cre,
  • Vav1 (HS21/5)-iCre,
  • VavCre,
  • VavCre,
  • VavCre<deBoer>,
  • Vav1 (HS21/5)-iCre,
  • Vav-iCre,
  • Tg(Vav1-cre)1Kio
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

17 Carried By

1 Driven By

603 Publication categories