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Allele : Chat<tm1Fhg> choline O-acetyltransferase; targeted mutation 1, Fred H Gage
Primary Identifier  MGI:2450310 Allele Type  Targeted
Attribute String  Null/knockout Gene  Chat
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S4/SvJae Is Recombinase  false
Is Wild Type  false
molecularNote  Exons 11, 12, and 13 were replaced with a neomycin selection cassette inserted by homologous recombination. Normal protein was undetected by immunostaining of the basal forebrain of homozygous mutant embryos. Assays of the brain stem, spinal cord, and septum showed an absence of endogenous activity.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ChAT(-),
  • ChAT(-)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories





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