Primary Identifier | MGI:2450311 | Allele Type | Transgenic |
Attribute String | Hypomorph, Recombinase | Gene | Tg(Tek-cre)1Ywa |
Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | This transgene expresses Cre recombinase under the control of a mouse Tek promoter and enhancer. This promoter is active in endothelial cells. Insertion within intron 1 of Sorcs2 results in the 204 bp deletion (36382105 to 36382309 on mouse chromosome 5; GRCm37/mm9 genome build) leading to reduced and variable expression. |