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Allele : Fmr1<tm2Cgr> fragile X messenger ribonucleoprotein 1; targeted mutation 2, Ben Oostra
Primary Identifier  MGI:2451086 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Fmr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The mouse promoter 8 CGG repeat sequence was replaced with a human 98 CGG repeat and a floxed neo cassette via homologous recombination. The targeted allele was verified by PCR analysis. Germline passage of this allele results in contraction and expansion of the CGG repeats.
  • mutations:
  • Nucleotide repeat expansion
  • synonyms:
  • CGG(98),
  • CGG(98)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

35 Publication categories





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