Primary Identifier | MGI:2651561 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Lifr |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Approximately 20 kb of endogenous sequence was replaced with an IRES-beta-geo cassette. The deleted sequence contained 7 exons encoding the cytokine receptor domains (amino acids 85 through 444). The expression pattern of the beta-galactosidase gene recapitulated that of the endogenous gene. |