Primary Identifier | MGI:2450875 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Soat2 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of 1.5 kb of 3' sequences with a neomycin resistance cassette by homologous recombination. The gene targeting event results in deletion of 28% of the protein coding sequence. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of mRNA from liver and small intestines. |