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Allele : Apoa1<tm1(APOA1)Prli> apolipoprotein A-I; targeted mutation 1, Cinzia Parolini

Primary Identifier  MGI:2451255 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Apoa1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 through 4 were either replaced or disrupted by the insertion of human APOA1 exons 2 through 4 via homologous recombination. Whereas murine exons 2 through 3 were replaced by the human sequence for exons 2-4, murine exon 4 was disrupted by a neomycin selection cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • A-I k-in,
  • A-I k-in
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories