| Primary Identifier | MGI:2653059 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ndn |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The 5' two-thirds of the endogenous coding region was replaced with a floxed neo cassette inserted by homologous recombination. Normal transcript was undetected by Northern blot and RT-PCR analyses of both homozygous mutant mice and heterozygous mice carrying a paternal mutant allele. An absence of protein was verified in these mice by Western blot analysis of brain tissue. |