| First Author | Kim CH | Year | 2005 |
| Journal | Nat Neurosci | Volume | 8 |
| Issue | 8 | Pages | 985-7 |
| PubMed ID | 16007085 | Mgi Jnum | J:101578 |
| Mgi Id | MGI:3604281 | Doi | 10.1038/nn1432 |
| Citation | Kim CH, et al. (2005) Persistent hippocampal CA1 LTP in mice lacking the C-terminal PDZ ligand of GluR1. Nat Neurosci 8(8):985-7 |
| abstractText | The C-terminal PDZ ligand of the AMPA receptor GluR1 subunit may be important for expression of CA1 hippocampal long-term potentiation. To test this directly in vivo, we generated a knock-in mouse lacking the last seven residues of GluR1, comprising the PDZ ligand. This deletion did not affect basal GluR1 synaptic localization, basal synaptic transmission, long-term potentiation or long-term depression, indicating that the ligand is not required for CA1 hippocampal synaptic plasticity. |
