| Help | About | Contact Us

Allele : Tg(SV40-Ahr)1Poe transgene insertion 1, Lorenz Poellinger

Primary Identifier	MGI:2654022	Allele Type	Transgenic
Attribute String	Constitutively active, Inserted expressed sequence	Gene	Tg(SV40-Ahr)1Poe
Strain of Origin	(C57BL/6 x CBA)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

The SV40 promoter and mouse Igh enhancer were used to drive a constitutively active form of the mouse Ahr gene deleted for amino acids 288-421 in the thymus and spleen. The mutant protein is defective in ligand binding.

mutations:
Insertion

synonyms:
CA-AhR,
CA-AhR

earliestPublication:
Andersson P, et al. (2002) A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc Natl Acad Sci U S A 99(15):9990-5

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74416631

MouseMine