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Allele : Kcnmb1<tm1Pong> potassium large conductance calcium-activated channel, subfamily M, beta member 1; targeted mutation 1, Olaf Pongs

Primary Identifier  MGI:2654278 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnmb1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Gene targeting was used to flank exon 1 with a floxed PGK-neo cassette on one side and a loxP site on the other side. Correctly targeted ES cells were transiently transfected with a cre-recombinase plasmid to delete exon 1. Absence of gene expression in homozygous mutant animals was confirmed by Northern blot and RT-PCR analysis.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • BKbeta1<->,
  • BKbeta1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories