| Primary Identifier | MGI:2652945 | Allele Type | Spontaneous |
| Gene | Kitl | Strain of Origin | Ednrb<S-12ThW> |
| Is Recombinase | false | Is Wild Type | false |
| description | Publication J:82263 incorrectly states the affected amino-acid as at position 47. Comparing with the coordinates of the N31Y32 deletion in KitlSl-5R also described there, this is not correct, since based on the nucleotide cDNA coordinates given in the paper, the two mutations are described as 15 codons apart, not 16. Also, SW:P20826 locates the arginine for this allele at position 71 (or 46 in mature protein) and the asparagine and tyrosine in KitlSl-5R residues at 56-57 (31-32 mature), so, 15 amino-acids apart. |
| molecularNote | Sequence analysis revealed a C-to-T transition at coding coordinate 211 resulting in a nonsense codon in place of arginine 46 in exon 4 (p.R46* in mature protein or p.R71* in pre-protein). A severely truncated protein product is expected to be expressed from this allele. |
