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Allele : Maf<Ofl> MAF bZIP transcription factor; opaque flecks in lens

Primary Identifier	MGI:2654153	Allele Type	Radiation induced
Gene	Maf	Inheritance Mode	Semidominant
Strain of Origin	(C3H/HeEl x 102/El)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

The mutation in this mouse was identified as a G to A transition resulting in the amino acid substitution R291Q in the basic region of the DNA binding domain.

mutations:
Single point mutation

synonyms:
J-361,
J-361

earliestPublication:
Lyon MF, et al. (2003) A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding. Hum Mol Genet 12(6):585-94

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

3 Publication categories

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