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Allele : Itgb1<tm1Ross> integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Robert S Ross

Primary Identifier	MGI:2656179	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Itgb1
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

LoxP sites were inserted into intron 1 and intron 3 by homologous recombination.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
beta1<flox>,
Itgb1<f>,
beta1 integrin-floxed,
Itgb1<f>,
beta1 integrin-floxed,
beta1<flox>

earliestPublication:
Shai SY, et al. (2002) Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res 90(4):458-64

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

12 Publication categories

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