Primary Identifier | MGI:2656470 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Il9 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4 was disrupted by homologous recombination of a targeting vector containing stop codons in all three reading frames and a neomycin selection cassette that replaces amino acids 54 through 59. Transcript was undetected by RT-PCR analysis of activated lymphocytes obtained from homozygous mutant mice. ELISA indicated the absence of protein in splenocyte cultures derived from homozygotes. |