Primary Identifier | MGI:2656714 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(2Gm13672-Hoxd11)68Ddu |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted 3' of Hoxd11 and a Hoxd9/lacZ/loxP transgene ( Tg(Hoxd9/lacZ/neo)4Ddu) was inserted 26 kb upstream of the Hoxd13 start site via homologous recombination. Mutant animals were mated to cre deleter line Tg(CMV-cre)1Ipc to delete the entire region between the 2 loxP sites, which includes Evx2, Hoxd13, Hoxd12, and Hoxd11. |